Family Report for: Est-OsmC
| Est-OsmC | Rank | 2 |
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| Family | Hydrolase_4 |
| Gene_locus (569) |
| Block | X |
| Paper | Jensen_2016_PLoS.One_11_e0166128 |
| | Al Khudary_2010_Extremophiles_14_273 |
| Structure | 5CML |
| Comment | composed of an N-terminal carboxylesterase domain and a C-terminal OsmC-like domain (osmotically induced family of proteins-like domain. This domain is not related to ABHD and excluded here. E.coli OsmC protein is able to metabolise peroxide, but in the Est-OsmC this activity is not found). Members of the family contained a second, less well conserved,GxSxG pentapeptide found 32 residues upstream of the completely conserved pentapeptide containing the active Serine. Two cysteine residues included in a putative substrate-binding region are found in the N-terminus. |
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