p.F295L/F297V Phe295Leu/Phe297Val (p.F326L/F328V Phe326Leu/Phe328Valin primary sequence with 31 amino-acids signal peptide) Acyl pocket, Increases hydrolysis of BTC OP-specificity: increases reactivity towards DFP DEFP and paraoxon;replacement of aromatic active center residues in human-ACHE by the corresponding residues in human-BCHE
