Paper

Tree Display

AceDB Schema

XML Display

Feedback

Paper Report for: Handrick_2001_J.Biol.Chem_276_36215

Name Class
Handrick_2001_J.Biol.Chem_276_36215Gene_locuspsele-PHAZ7
FamilyLipase_2
PHAZ7_phb_depolymerase
Reference (5)
CommentThe original classification of bacterial lypolytic enzymes by Arpigny and Jaeger was updated by Jaeger and Eggert in 2002, Hausmann and Jaeger (2010), Kovacic, Krauss and Jaeger (2019). See the correspondance with ESTHER (Table). 6 out of the 8 families described in the orginal paper by Arpigny and Jaeger belong to alpha beta hydrolases. (I III Bacterial_lipase, IV HSL Hormone-sensitive_lipase_like, V Pha_depolymerase, VI LYsophospholipase_carboxylesterase, VII Carboxylesterase). Family II is the closely related GDSL family and family VIII is beta lactamase with sequences which contain a GXSXG motif in the c-terminal part of the protein but are not alpha-beta hydrolases. The original classification in 8 families was further extended. Family I was subdivided in 7 subfamilies by Jaeger and Eggert (2002). Family IX was introduced by Handrick et al.(2001). Family X was introduced by Levisson et al. 2007, Bassegoda et al. 2012). Family XI was introduced by Lee et al.(2006). Family XII was introduced by Kim et al. (2009) Family XIII was introduced by Ewis et al.(2004) and Liu et al.(2004) and was divided in two by Charbonneau et al.(2013) Family XIV was introduced by Rao et al.(2011). Family XV was introduced by Bayer et al.(2010) and Lee et al. (2010). Family XVI was introduced by Fu et al.(2013)
Author (7)
Medline11457823
AbstractHandrick_2001_J.Biol.Chem_276_36215
SubstratePHB
Arpigny_JaegerFamily_IX

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer