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Family Report for: Homoserine_transacetylase_like_est

Name Class
Homoserine_transacetylase_like_estRank2
FamilyAbhydrolase_6
Gene_locus (14)
BlockX
PaperTolzer_2016_FEBS.Lett_590_174
Structure (7)
InterproIPR008220 Homoserine/serine acetyltransferase MetX-like HAT_MetX-like
IPR000073 Alpha/beta hydrolase fold-1
CommentToelzer et al. showed that MekB (9psed-q0mrg5) from Pseudomonas veronii and CgHle (corgl-CGL0839) from Corynebacteriumglutamicum are esterases that hydrolyse preferentially acetic acid esters. MekB and CgHle cannot bind homoserine and acetyl-CoA. Accordingly a novel esterase subfamily was extracted from the Homoserine_transacetylase family
PfamPF00561 Abhydrolase_1
PIRSFPIRSF000443 homoserine acetyltransferase
SubstrateEthylacetate
Paranitrophenylacetate
Vinyl-acetate

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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