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Inhibitor Report for: IMP-MeCyC

Name Class
IMP-MeCyCType (5)
Other_Namemethylphosphonic acid 3-cyano-7-hydroxy-4-mehtyl-2oxo-2H-coumarin-7-yl ester isopropyl ester
Chemical_Nomenclature4-methyl-7-[methyl(propan-2-yloxy)phosphoryl]oxy-2-oxochromene-3-carbonitrile
FormulaC15H16NO5P
MW321.27
PaperAmitai_2006_Febs.J_273_1906
Amitai_2007_Toxicology_233_187
Mangas_2016_Arch.Toxicol_90_603
CommentCoumarin
Sarin analogue. Fluorogenic organophosphate diesters that produce fluorescence emission upon hydrolysis. The first ester is ethyl (E), isopropyl (I), cyclohexyl (C) or pinacoyl (P) analogous to the structure of VX, Sarin, Cyclosarin, and Somen respectively. The fluorescent ester is 3-cyano-4-methyl-7-hydroxy coumarin (MeCyC) or 1,3-dichloro-7-hydroxy-9,9-dimethyl-9H-acridin-2-one (DDAO)
CID49795036
FamilyACHE
InChIKeyDQOLUZOTNSTJCY-UHFFFAOYSA-N
CanonicalSMILESCC1=C(C(=O)OC2=C1C=CC(=C2)OP(=O)(C)OC(C)C)C#N
InChIInChI=1S/C15H16NO5P/c1-9(2)20-22(4,18)21-11-5-6-12-10(3)13(8-16)15(17)19-14(12)7-11/h5-7,9H,1-4H3

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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