Substrate Report for: Imidapril
Imidapril | Type | Pro-Drug |
| | Drug |
| | Not A/B H target |
| Other_Name (8) |
| Chemical_Nomenclature | (4S)-3-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid |
| Formula | C20H27N3O6 |
| CAS_number | 89371-37-9 |
| MW | 405.4 |
| |
| Paper (11) |
| Comment | Imidapril is a prodrug. imidapril is converted by human-CES1 (not CES2 or AADAC) into its active form imidaprilat: an angiotensin-converting enzyme (ACE) inhibitor |
| Gene_locus | human-CES1 |
| CID | 5464343 |
| Family | Carb_B_Chordata |
| InChIKey | KLZWOWYOHUKJIG-BPUTZDHNSA-N |
| CanonicalSMILES | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C(CN(C2=O)C)C(=O)O |
| InChI | InChI=1S/C20H27N3O6/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26)/t13-,15-,16-/m0/s1 |
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