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News Report for: July-06-2022

Name Class
July-06-2022PaperLillich_2021_J.Med.Chem_64_17259
Arellano-Saab_2022_J.Biol.Chem_298_101734
Do_2022_Crystals_12_46
Shen_2022_Drug.Metab.dispos__
Structure (7)
Number727
DateJuly 06, 2022
Comment Structure-based design of dual partial peroxisome proliferator-activated receptor gamma agonists/Soluble epoxide hydrolase inhibitors is published by Lillich et al. and structure of soluble epoxide hydrolase in complex with FL217 (7P4K) is available A novel strigolactone receptor antagonist providing insights into the structural inhibition, conditioning, and germination of the crop parasite Striga is published by Arellano-Saab et al. and crystal structure of ShHTL7 from Striga hermonthica in complex with strigolactone antagonist RG6 (7SNU),is available. Crystal structure of BioH3 from Mycolicibacterium smegmatis (7WWF) is available and will be published soon by Yang et al. Structures of Omphalotus olearius (Jack o'lantern) macrocyclase OphP prolyl oligopeptidase (7ZAZ, 7ZB0, 7ZB1, 7ZB2) are available and will be published soon by Song, H. and Naismith, J.H. Sequence analysis and preliminary X-ray crystallographic analysis of an acetylesterase (LgEstI) from Lactococcus garvieae are published by Do et al. Shen et al. show that the Covid-19 oral drug Molnupiravir is a CES2 substrate: Potential drug-drug interactions and impact of CES2 polymorphism in vitro

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