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Mutation Report for: K469R_human-BCHE

Name Class
K469R_human-BCHEGene_locushuman-BCHE
Torpedo_number471
AA_ChangeK469R
Mode_of_mutationSite directed mutagenesis
Modification (2)
SummaryPROSS algorithm;Expression in E Coli;Brazzolotto_2017_Molecules_22_
PaperBrazzolotto_2017_Molecules_22_
Structure6EMI
Commentp.K469R Lys469Arg (p.K497R Lys497Arg in primary sequence with 28 amino-acids signal peptide) Mutation designed by -Protein Repair One Stop Shop- process for the production of active human butyrylcholinesterase in a prokaryotic system. The mutation gives Arg as in ACHE of Bungarus fasciatus

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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