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Inhibitor Report for: Leupeptin

Name Class
LeupeptinTypePeptide
Natural
Other_Name (10)
Chemical_Nomenclature(2S)-2-acetamido-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
FormulaC20H38N6O4
CAS_number24365-47-7
MW426.55
PaperMcLuskey_2010_J.Biol.Chem_285_39249
CommentLeupeptin is a protease inhibitor produced by actinomycetes, that can inhibit cysteine, serine and threonine peptidases
CID72429
FamilyS9N_PREPL_Peptidase_S9
InChIKeyGDBQQVLCIARPGH-ULQDDVLXSA-N
CanonicalSMILESCC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C
InChIInChI=1S/C20H38N6O4/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23)/t15-,16-,17-/m0/s1
WikipediaLeupeptin

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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