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News Report for: MAY-01-2002

Name Class
DateMay 1, 2002
Comment A new family has been introduced. The new structure (09-JAN-2002!!? Tsai et al. 2001) is 1KEZ An interesting feature is a substrate channel that passes through the entire protein. Thioesterase domains often occur integrated in or associated with peptide synthetases which are involved in the non-ribosomal synthesis of peptide antibiotics. Thioesterases are required for the addition of the last amino acid to the peptide antibiotic, thereby forming a cyclic antibiotic.Only the last domain TE thioesterase of the acv synthetase (acvs) is included in ESTHER

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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