Inhibitor Report for: MC1420
| MC1420 | Type | Derivative of Donepezil |
|---|
| | Carboxamide |
| Other_Name | N9T |
| Chemical_Nomenclature | (1R,3S)-3-(Benzylamino)-N-(6,7-dimethoxy-2-oxochromen-3-yl)cyclohexane-1-carboxamide |
| Formula | C25H28N2O5 |
| MW | 436.5 |
|  |
| Paper | Catto_2020_ACS.Med.Chem.Lett_11_869 |
| Structure | 6TT0 |
| Comment | Potent and reversible dual binding site AChE inhibitor |
| Gene_locus | torca-ACHE |
| CID | 71508421 |
| Family | ACHE |
| InChIKey | UGTGSTDFYWUXNH-MJGOQNOKSA-N |
| CanonicalSMILES | COC1=C(C=C2C(=C1)C=C(C(=O)O2)NC(=O)C3CCCC(C3)NCC4=CC=CC=C4)OC |
| InChI | InChI=1S/C25H28N2O5/c1-30-22-13-18-12-20(25(29)32-21(18)14-23(22)31-2)27-24(28)17-9-6-10-19(11-17)26-15-16-7-4-3-5-8-16/h3-5,7-8,12-14,17,19,26H,6,9-11,15H2,1-2H3,(H,27,28)/t17-,19+/m1/s1 |
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