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Inhibitor Report for: MT-031
Name
Class
MT-031
Type
Monoamine-oxidase-inhibitor
Multitarget
Carbamate
Other_Name
(S)-3-(1-(Methyl(prop-2-yn-1-yl)amino)ethyl)phenyl ethyl(methyl)carbamate
SCHEMBL16948183
Chemical_Nomenclature
[3-[(1R)-1-[methyl(prop-2-ynyl)amino]ethyl]phenyl] N-ethyl-N-methylcarbamate
Formula
C16H22N2O2
CAS_number
1802158-63-9
MW
274.36
Paper
Liu_2016_Neuropharmacol_109_376
Liu_2022_Ageing.Neurodegener.Dis__
Comment
mild inhibitor of ACHE IC50 58.3 +/- 6.3 microM and BCHE 34.6 +/- 8.3 microM
Gene_locus
human-ACHE
human-BCHE
CID
118266847
Family
ACHE
BCHE
InChIKey
ALHSEIIOFXOKLH-CYBMUJFWSA-N
CanonicalSMILES
CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)CC#C
InChI
InChI=1S/C16H22N2O2/c1-6-11-18(5)13(3)14-9-8-10-15(12-14)20-16(19)17(4)7-2/h1,8-10,12-13H,7,11H2,2-5H3/t13-/m1/s1
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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