News Report for: March-02-2022
| March-02-2022 | Paper | Yang_2022_Biochem.Biophys.Res.Commun_600_117 |
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| | Sun_2022_Proc.Natl.Acad.Sci.U.S.A_119_ |
| | Ekstrom_2022_ACS.Med.Chem.Lett_13_499 |
| | Zhang_2022_Front.Microbiol_12_803896 |
| Structure (28) |
| Number | 709 |
| Date | March 02, 2022 |
| Comment |  Structure-guided rational design of the Geobacillus thermoglucosidasius feruloyl esterase GthFAE to improve its thermostability is published by Yang et al. and structure (7WWH) will be available soon  Dual reversible coumarin inhibitors mutually bound to monoamine oxidase B and acetylcholinesterase crystal structures are published by Ekstrom et al. and structures will be available soon (7QAK, 7QB4) Structure of human Pectinacetylesterase-Notum in complex with inhibitors are available (7BLI, 7BLS, 7BLT, 7BLU, 7BLW, 7BM1, 7BM3, 7BM7, 7BMB, 7BMD, 7BN5, 7BN8, 7BNB, 7BNC, 7BND, 7BNE, 7BNF, 7BNJ, 7BNL, 7BO1, 7BO2, 7BO5) and will be published soon by Zhao and Jones. Human Butyrylcholinesterase in complex with N-(2-(1H-Indol-3-yl)ethyl)-2-cycloheptyl-N-methylethan-1-amine and 3-(2-(butyl(2-cycloheptylethyl)amino)ethyl)-1H-indol-6-ol are available (7BO3, 7BO4) and will be published soon by Brazzolotto et al. Crystal structure of haloalkane dehalogenase LinB57 mutant (H272F) from Sphingobium japonicum UT26 is available (7NFZ) and will be published soon by Marek, M., and Damborsky, J. Structure of a bacteroidetal polyethylene terephthalate (PET) esterase PET30 is published by Zhang et al. and is available (7PZJ). Promiscuous esterases with PET-Hydrolyzing activity are also described. Sun et al. published that Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model. Structure of soluble epoxide hydrolase (sEH) in complex with Kurarinone will be available soon (7EBA). |
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