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News Report for: March-03-2021

Name Class
March-03-2021Paper (7)
Structure (14)
Number658
DateMarch 03, 2021
Comment Zao et al. published that Notum deacylates octanoylated ghrelin andadd Notum to the list of enzymes, including butylcholineasterase, that modulate the acylation state of ghrelin. Structure of the Notum-ghrelin complex will be available soon (6ZYF) Synthesis and initial characterization of a selective, pseudo-irreversible inhibitor of Human Butyrylcholinesterase as PET tracer is published by Gentzsch et al. Production of Cross-Linked Lipase Crystals at a Preparative Scale is published by Fernandez-Penas et al. and structures are available (7APN, 7APP) Structure of E125A mutant of oligopeptidase B from S. proteomaculans with modified hinge region is available (7NE4) and will be published soon by Petrenko et al. Biochemical and structural characterization of a novel thermophilic esterase EstD11 provide catalytic insights for the HSL family is published by Miguel-Ruano et al. and structures are available (7ATD, 7ATF, 7AT2, 7AT3, 7AT4, 7AT0, 7ATQ, 7AV5, 7AUY, 7NB5) A review on regulators of cholinergic signaling in disorders of the central nervous system is published by Winek et al. and one on ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical by Taylor et al. Ramesh et al. published that antagonistic interactions between two Neuroligins coordinate pre- and postsynaptic assembly

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