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News Report for: May-11-2022

Name Class
May-11-2022Paper (3)
DateMay 11, 2022
Comment Crystal structure of Epiphyas postvittana antennal carboxylesterase 24 is available (7MP4) and will be published soon by Hamiaux et al. Willis et al. describe the design of a potent, selective and brain penetrant inhibitor of Wnt-deactivating enzyme Notum (ARUK3001185) by optimization of a crystallographic fragment hit. A structure will be available soon (7PK3) Crystal structure of human acetylcholinesterase in complex with tacrine and implications for drug discovery is published by Dileep et al. and structure (7XN1) is available Zorbaz et al. publish that halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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