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Substrate Report for: N-(3-Carboxy-4-nitrophenyl)phthalamidic-acid

Name Class
N-(3-Carboxy-4-nitrophenyl)phthalamidic-acidTypepNP
Phthalate
Other_NameN-(3-Carboxy-4-nitrophenyl)phthalamidic acid
Chemical_Nomenclature5-[(2-carboxybenzoyl)amino]-2-nitrobenzoic acid
FormulaC15H10N2O7
MW330.25
PaperBriggs_1996_J.Mol.Catal.B.Enzym_2_53
Black_1996_Biotechnol.Lett_18_875
CommentChromogenic substrate to analyze . o-phthalyl amidase. Phthalimido is a stable protecting group in beta-lactam chemistry but no conventional chemical methods effectively removes this group. xanag-pham catalyzes the removal of the phthalyl group from phthalyl amides generating phthalate and an amine. The enzyme has a broad substrate specificity and hydrolyzes phthalylated amino acids, peptides, beta-lactams, aromatic and aliphatic amines
Gene_locusxanag-pham
CID102001082
Family6_AlphaBeta_hydrolase
InChIKeyZQXCSGXRVQMUMI-UHFFFAOYSA-N
CanonicalSMILESC1=CC=C(C(=C1)C(=O)NC2=CC(=C(C=C2)[N+](=O)[O-])C(=O)O)C(=O)O
InChIInChI=1S/C15H10N2O7/c18-13(9-3-1-2-4-10(9)14(19)20)16-8-5-6-12(17(23)24)11(7-8)15(21)22/h1-7H,(H,16,18)(H,19,20)(H,21,22)

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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