ESTHER Database

Home
Search
Text search
aql query
In Class
Query Builder
Preformed queries
Species
Structures
Mutations
Interactants
Diseases
Genes
Insecticides
Other
Full List
Queries for insecticide resistance
AQL exemples
Tools
Blast
HMMER
Clustal
Psiblast
Intra
Families
Overall Table
Tree Table &
Old Table
Tree Table
Old Table
Explore genes with AQL
Explore species with AQL
All figures of families
Biological
data
Structures
Table
Explore structure with AQL
Mutations
Mutation Viewer
Mutalign
Mutalign 2
Mutalign for insecticide resistance
Queries for insecticide resistance
Explore mutation with AQL
Interactants
Substrates
Inhibitors
Reactivators
Kinetic comparison tool
Inhibitor types
Substrate types
Reactivator types
Explore interactants with AQL
Diseases
Table
Explore disease with AQL
Basics on AChE
Kinetics notes
Gene structures
Molecular forms
AChE Family
Human AChE
ESTHER definition
What is up?
Likid
DB Explorer
Meetings
Suplementary Data
Latest modifications
Bibliography (all years)
Acknowledgments
& disclaimer



Mutation
Kinetic parameters
Tree Display
AceDB Schema
XML Display
Feedback

Mutation Report for: N68D_human-BCHE

Name Class
N68D_human-BCHEGene_locushuman-BCHE
Torpedo_number70
AA_ChangeN68D
Mode_of_mutationSite directed mutagenesis
ModificationPeripheral Anionic Site
SummaryPeripheral Anionic Site;vKi BW284C51;Loewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423
PaperLoewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423
Kinetic_parameterButyrylthiocholine_N68D_human-BCHE
Tacrine_N68D_human-BCHE
Succinylcholine~Suxamethonium_N68D_human-BCHE
Dibucaine_N68D_human-BCHE
Solanine_N68D_human-BCHE
BW284C51_N68D_human-BCHE
Commentp.N68D Asn68Asp (p.N96D Asn96Asp in primary sequence with 28 amino-acids signal peptide) lower Ki with BW284C51
Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer