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News Report for: NOVEMBER-01-2017

Name Class
NOVEMBER-01-2017PaperBrazzolotto_2017_Molecules_22_
Czekster_2017_Nat.Commun_8_1045
Jones_2017_Biochemistry_56_6521
Structure (6)
Number496
DateNovember 01, 2017
CommentBacterial expression of human butyrylcholinesterase as a tool for nerve agent bioscavengers development is published by Brazzolotto et al. and structure will be available soon (6EMI). The mutated human BChE was designed using the PROSS algorithm of Goldenzweig et al..Some tables of the mutations are available in table. This paper belongs to the special issue in the Journal Molecules : The Cholinesterases - Structure, Mechanism, Function and Drug Design: The 25th Anniversary of the Solution of the Crystal Structure of Acetylcholinesterase by Joel L. Sussman and Israel Silman with the guest editors: Prof. Anthony H. Futerman, Dr. Yacov Ashani, Dr. Gabriel (Gabi) Amitai, Dr. Lev Weiner. A list of the papers is found here LIST. Structures of Galerina marginata Prolyl oligopeptidase are available (5N4B, 5N4C, 5N4D, 5N4E, 5N4F) and published by Czekster et al. Comparison of five protein engineering strategies to stabilize an alpha/beta-hydrolase is published by Jones et al.

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