Crystal structures of mutants of an epoxide hydrolase from Bacillus megaterium (4NZZ, 4O08) are available and published by Kong et al.. They identified an active tunnel for substrate access and product release of this enzyme. Structural and biochemical characterization of a metagenome-derived esterase with a long N-terminal extension is published by Okano et al. and will be available soon (3WYD)