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Substrate Report for: OphMA-core-peptide-15mer

Name Class
OphMA-core-peptide-15merTypePeptide
Macrocycle
PaperMatabaro_2021_Sci.Rep_11_3541
Matabaro_2021_Methods.Enzymol_656_429
Ramm_2017_Angew.Chem.Int.Ed.Engl_56_9994
Matabaro_2022_bioRxiv__
Structure7ZB0
CommentBackbone N-methylated, macrocyclic dodecapeptides produced by the mushroom Omphalotus olearius. Omphalotins display a strong and selective toxicity toward the plant parasitic nematode Meloidogyne incognita. N-methylated peptide macrocycle omphalotin A (nematicidal cyclododecapeptide). A methyltransferase OphMA that catalyzes the automethylation of its C-terminus, which is then released and cyclized by the protease OphP
Gene_locusompol-OphP
FamilyS9N_PPCE_Peptidase_S9

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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