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Type_substrate Report for: Organophosphate

Name Class
OrganophosphateSubstrate (10)
CommentMany inhibitors are in fact substrates very slowly hydrolyzed. Organophosphates (also known as phosphate esters OP) are a class of organophosphorus compounds with the general structure O=P(OR)3. They can be considered as esters of phosphoric acid. Here we consider only those compounds that interact with alpha/beta hydrolases mostly as inhibitors (insecticides, nerve agents etc...). As the number of compounds increases in the database you can choose to select subsets such as: Chemical Warfare Agent or more precisely: Nerve Agent G-series, Nerve Agent V-series, Derivative of Sarin, Derivative of Soman, Surrogate OP, Organothiophosphate, Phosphonylatedoxime, or pesticides (including compounds not OP): Herbicide, Insecticide, Anthelmintic, or investigational compounds: Cyclic OP, ABPP-Probe, Flu-OP. You can also search another category of compounds in the list: Types of inhibitors

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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