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Family Report for: Prolyl_oligopeptidase_S9

Name Class
Prolyl_oligopeptidase_S9Rank2
FamilyPeptidase_S9
Gene_locus (189)
Gene_locus_Frgt9arch-d1jiq6
cocpo-q3i3b2
leima-Q9NJT9
playo-q7rps0
schja-q5dep6
tryb2-q57z19
9sphn-a0a0n0k3g4
9sphn-a0a117usg9
BlockX
PaperBrocca_2016_FEBS.J_283_4310
Beauvais_1997_J.Biol.Chem_272_6238
Structure5L8S
3KSR
InterproIPR001375 Peptidase_S9
CommentProlyl_oligopeptidase_S9 are serine protease of the clan S family S9 in MEROPS database. Previously this family contained also all the subfamilies ACPH_Peptidase_S9, Glutamyl_Peptidase_S9, DPP4N_Peptidase_S9, S9N_Peptidase_S9. Now it contains entries that do not fit in these well defined sub families. Few proteins characterized in this family. Aspergillus fumigatus DPP5 and DPP4 (Beauvais et al.) DPP5 unique substrate specificity limited to the hydrolysis of X-Ala, His-Ser, and Ser-Tyr dipeptide and not post Proline
PfamPF00326 Peptidase_S9
MEROPSS9A
Substrate (5)

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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