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Family Report for: Prolyl_oligopeptidase_S9

Name Class
Prolyl_oligopeptidase_S9Rank2
FamilyPeptidase_S9
Gene_locus (189)
Gene_locus_Frgt (8)
BlockX
PaperBrocca_2016_FEBS.J_283_4310
Beauvais_1997_J.Biol.Chem_272_6238
Structure5L8S
3KSR
InterproIPR001375 Peptidase_S9
CommentProlyl_oligopeptidase_S9 are serine protease of the clan S family S9 in MEROPS database. Previously this family contained also all the subfamilies ACPH_Peptidase_S9, Glutamyl_Peptidase_S9, DPP4N_Peptidase_S9, S9N_Peptidase_S9. Now it contains entries that do not fit in these well defined sub families. Few proteins characterized in this family. Aspergillus fumigatus DPP5 and DPP4.(Beauvais et al.) DPP5 unique substrate specificity limited to the hydrolysis of X-Ala, His-Ser, and Ser-Tyr dipeptide and not post Proline
PfamPF00326 Peptidase_S9
MEROPSS9A
Substrate (5)

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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