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Inhibitor Report for: Pyridophen-10

Pyridophen-10	Type (7)
	Other_Name (5)
	Chemical_Nomenclature	[3-(dimethylcarbamoyloxy)-1-methylpyridin-1-ium-2-yl]methyl 2,2-diphenylpropanoate
	Formula	C25H27N2O4+
	MW	419.5
	Paper	Wang_2005_Bioorg.Med.Chem.Lett_15_4510
		Leader_2002_J.Med.Chem_45_902
	Comment	Inhibits AChE selectively over BChE, with a bimolecular rate constant similar to pyridostigmine. [11C]MDDP; N-[11C]Methyl-3-[[(dimethylamino)carbonyl]oxy]-2-(2',2'-diphenylpropionoxymethyl)pyridinium. Used as PET imaging of a novel potential heart acetylcholinesterase tracer by Wang et al.
	CID	10482128
		11734279
		10482127
		16040296
	Family	ACHE
	InChIKey	WHIMEOMPXHBKBV-UHFFFAOYSA-N
	CanonicalSMILES	CC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OCC3=C(C=CC=[N+]3C)OC(=O)N(C)C
	InChI	InChI=1S/C25H27N2O4/c1-25(19-12-7-5-8-13-19,20-14-9-6-10-15-20)23(28)30-18-21-22(16-11-17-27(21)4)31-24(29)26(2)3/h5-17H,18H2,1-4H3/q+1