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Inhibitor Report for: Pyrrolidine-10-6YV0

Pyrrolidine-10-6YV0	Type	Pyrrole_Pyrrolidine-derivative
	Other_Name	Pyrrolidine-3-carboxylic acid fragment 587
		PQT
		(3~{R})-1-(2-chlorophenyl)pyrrolidine-3-carboxylic acid
		ZINC84499328
	Chemical_Nomenclature	(3R)-1-(2-chlorophenyl)pyrrolidine-3-carboxylic acid
	Formula	C11H12ClNO2
	MW	225.67
	Paper	Mahy_2020_J.Med.Chem_63_9464
	Structure	6YV0
	Comment	IC50 19 +/- 14 microM Notum with OPTS substrate
	Gene_locus	human-NOTUM
	CID	97013871
	Family	Pectinacetylesterase-Notum
	InChIKey	FPGYADRKFPWWLU-MRVPVSSYSA-N
	CanonicalSMILES	C1CN(CC1C(=O)O)C2=CC=CC=C2Cl
	InChI	InChI=1S/C11H12ClNO2/c12-9-3-1-2-4-10(9)13-6-5-8(7-13)11(14)15/h1-4,8H,5-7H2,(H,14,15)/t8-/m1/s1