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Mutation Report for: Q642-644del_bacol-ACHE

Name Class
Q642-644del_bacol-ACHEGene_locusbacol-ACHE
Torpedo_number551
553
554
551,553,554
AA_ChangeQ642-644del
Mode_of_mutationNatural mutant
ModificationOP-resistance
SummaryOP-resistance;found associated with resistance;Kakani_2008_Insect.Biochem.Mol.Biol_38_781
OP-resistance;OP-resistance (omethoate);Kakani_2011_Insect.Biochem.Mol.Biol_41_150
Paper (5)
Commentthe deletion of 3 Q may improve GPI anchoring thus increasing the amount of AChE that reaches the synaptic cleft
a short deletion of three glutamines Delta3Q from a stretch of five glutamines in the C-terminal peptide that is normally cleaved and substituted by a GPI anchor

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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