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Inhibitor Report for: Rhc80267

Name Class
Rhc80267TypeCarbamate
Other_Name (6)
Chemical_Nomenclature(cyclohexylideneamino) N-[6-[(cyclohexylideneamino)oxycarbonylamino]hexyl]carbamate
FormulaC20H34N4O4
MW394.50
Paper (9)
CommentInhibitor of DAGL but inhibits also ABHD6 HSL MGLL and CES1. However Baggelaar et al.2013 found no inhibition of DAGLA
Gene_locushuman-DAGLA
human-DAGLB
CID5063
Family (5)
InChIKeyRXSVYGIGWRDVQC-UHFFFAOYSA-N
CanonicalSMILESC1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1
InChIInChI=1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26)
IupharLig5255

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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