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Inhibitor Report for: Ru-NHC-3

Name Class
Ru-NHC-3TypeOrganophosphate
Pincer-Metal-cofactor
pNP
FormulaC43H55Cl2N3O6PRu
MW912,86
PaperBasauri-Molina_2015_Chemistry_21_15676
CommentThe incorporation of a synthetic, catalytically competent metallo cofactor into a protein scaffold to generate an artificial metalloenzyme (ArM) lead to new activities specific of the cofactor. Here NHC= N-heterocyclic carbenes Grubs-type catalyst with organophosphate function, inhibits cutinase and forms an artificial metalloenzyme for olefin metathesis
Gene_locusfusso-cutas
FamilyCutinase

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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