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News Report for: SEPTEMBER-04-2013

Name Class
SEPTEMBER-04-2013PaperAndersson_2013_J.Med.Chem_56_7615
Devasthale_2013_J.Med.Chem_56_7343
Ngo_2013_Acta.Crystallogr.D.Biol.Crystallogr_69_1726
Structure (11)
Number310
DateSeptember 04, 2013
CommentStructures of acetylcholinesterase with two compound classes consisting of N-[2-(diethylamino)-ethyl]-benzenesulfonamides and N-[2-(diethylamino)-ethyl]-benzenemethanesulfonamides are published by Andersson et al. and are available (4B7Z, 4B80, 4B81, 4B82, 4B83, 4B84, 4B85, 4BTL). Crystal structure of dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) (DPP-IV-WT) complex with bms-767778 AKA 2-(3-(aminomethyl)-4-(2,4- dichlorophenyl)-2-methyl-5-oxo-5,7-dihydro-6h-pyrrolo[3,4- b]pyridin-6-yl)-n,n-dimethylacetamide and crystal structure of human DPP-IV in complex with BMS-744891 are available (4JH0, 4LKO)and published by Devasthale et al. Structure of a bacterial homologue of hormone-sensitive lipase from a metagenomic library Est25 is published by Ngo et al. and will soon be available (4J7A)

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