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Inhibitor Report for: SUMO1-EIL

Name Class
SUMO1-EILTypePeptide
Other_NameSLRFLFEGQRIADNH
E67 interacting loop (EIL)
BDBM213827
Chemical_NomenclatureSLRFLFEGQRIADNH
FormulaC80H123N25O23
MW1803
Pick_me_to_calldisplay_scriptSUMO1-EIL
PaperPilla_2013_J.Biol.Chem_288_32787
Ross_2021_J.Appl.Crystallogr_54_895
Structure6TRW
CommentThe small ubiquitin-like protein modifier SUMO1 interacts with an armlike structure in DPP8 DPP9, leading to allosteric activation of the peptidase. SUMO1-EIL noncompetitive Inhibitor of DPP8 and DPP9 - E67 interacting loop (EIL)
Gene_locushuman-DPP8
human-DPP9
CID124220806
FamilyDPP4N_Peptidase_S9

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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