ESTHER
Database
Home
Search
Text search
aql query
In Class
Query Builder
Preformed queries
Species
Structures
Mutations
Interactants
Diseases
Genes
Insecticides
Other
Full List
Queries for insecticide resistance
AQL exemples
Tools
Blast
HMMER
Clustal
Psiblast
Intra
Families
Overall Table
Tree Table &
Old Table
Tree Table
Old Table
Explore genes with AQL
Explore species with AQL
All figures of families
Biological
data
Structures
Table
Explore structure with AQL
Mutations
Mutation Viewer
Mutalign
Mutalign 2
Mutalign for insecticide resistance
Queries for insecticide resistance
Explore mutation with AQL
Interactants
Substrates
Inhibitors
Reactivators
Kinetic comparison tool
Inhibitor types
Substrate types
Reactivator types
Explore interactants with AQL
Diseases
Table
Explore disease with AQL
Basics on AChE
Kinetics notes
Gene structures
Molecular forms
AChE Family
Human AChE
ESTHER definition
What is up?
Likid
DB Explorer
Meetings
Suplementary Data
Latest modifications
Bibliography (all years)
Acknowledgments
& disclaimer
Inhibitor
Bibliography
Biblio print
Tree Display
AceDB Schema
XML Display
Feedback
Inhibitor Report for: SUMO1-EIL
Name
Class
SUMO1-EIL
Type
Peptide
Other_Name
SLRFLFEGQRIADNH
E67 interacting loop (EIL)
BDBM213827
Chemical_Nomenclature
SLRFLFEGQRIADNH
Formula
C80H123N25O23
MW
1803
Pick_me_to_call
display_script
SUMO1-EIL
Paper
Pilla_2013_J.Biol.Chem_288_32787
Ross_2021_J.Appl.Crystallogr_54_895
Structure
6TRW
Comment
The small ubiquitin-like protein modifier SUMO1 interacts with an armlike structure in DPP8 DPP9, leading to allosteric activation of the peptidase. SUMO1-EIL noncompetitive Inhibitor of DPP8 and DPP9 - E67 interacting loop (EIL)
Gene_locus
human-DPP8
human-DPP9
CID
124220806
Family
DPP4N_Peptidase_S9
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page
and
ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster
Acknowledgements and disclaimer