Inhibitor Report for: Sarin
Sarin | Type | Chemical Warfare Agent |
| | Organophosphate |
| | Nerve Agent G-series |
| | Derivative of Sarin |
| Other_Name (11) |
| Chemical_Nomenclature | 2-[fluoro(methyl)phosphoryl]oxypropane |
| Formula | C4H10FO2P |
| CAS_number | 107-44-8 |
| MW | 140.09 |
| |
| Paper (48) |
| Structure (12) |
| Comment | The organophosphate nerve agents tabun (GA), sarin (GB), soman (GD), and cyclosarin (GF) are among the most toxic chemical warfare agents known. The G-series nerve agents are named because German scientists led by Dr Gerhard Schraderfirst synthesized them during World War II, beginning with GA in 1936. GB was discovered next in 1938, followed by GD in 1944 and finally GF in 1949. The only other known nerve agent, O-ethyl S-(2-diisopropylaminoethyl) methylphosphonothioate (VX), V-series - VE, VG, VM, Russian VX). G-series nerve agents share a number of common physical and chemical properties. At room temperature, the G-series nerve agents are volatile liquids, making them a serious risk for 2 types of exposure: dermal contact with liquid nerve agent or inhalation of nerve agent vapor.Sarin is an acronym for the names of the members of the development team: Schrader. Ambrose. Rudriger. and van der Linde. The Germans deignated it T-I44 or Trilon-46. The United Slates eventually designated it GB |
| Gene_locus | human-ACHE |
| | human-BCHE |
| | human-CTSA |
| CID | 7871 |
| Family | ACHE |
| | BCHE |
| | PAF-Acetylhydrolase |
| | Carboxypeptidase_S10 |
| InChIKey | DYAHQFWOVKZOOW-UHFFFAOYSA-N |
| CanonicalSMILES | CC(C)OP(=O)(C)F |
| InChI | InChI=1S/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3 |
| Wikipedia | Sarin |
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