A preprint by Menden et al. describes pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead. Structure of BCHE inhibited by one of the compound will be available soon (8AI7) Moore et al. publish a phenotypic screen identifying potent DPP9 inhibitors capable of killing HIV-1 infected cells. Structures of DPP8 and DPP9 with these compounds will be published soon (7SVO, 7SVM, 7SVN, 7SVL) The last structures of the Wnt deacylase Notum in complex with ARUK3001185 and ARUK3000223 (Compound 7b) published by Zhao et al. are available (7PK3, 7PKV) and new ones will be soon published (7PJR)