Type_substrate Report for: Trifluoro
| Trifluoro | Substrate | Fluazifop-butyl |
|---|
| | Lactofen |
| | Flutamide |
| | o-NTFNAC |
| | trans-Bifenthrin |
| | Ala-Pro-AFC |
| Comment | Building block for many synthetic substrates of enzymes. The trifluoromethyl group is a functional group that has the formula -CF3. The naming of is group is derived from the methyl group (which has the formula -CH3). The trifluoromethyl group is often used as a bioisostere to create derivatives by replacing a chloride or a methyl group. This can be used to adjust the steric and electronic properties of a lead compound, or to protect a reactive methyl group from metabolic oxidation. |
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