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Mutation Report for: W121A_drome-ACHE

Name Class
W121A_drome-ACHEGene_locusdrome-ACHE
Torpedo_number84
AA_ChangeW121A
Mode_of_mutationSite directed mutagenesis
ModificationBinding of Triton X-100 studies
Insecticide sensitivity
Back door hypothesis
SummaryBinding of Triton X-100 studies;no effect on Triton X-100 binding;Marcel_2000_J.Biol.Chem_275_11603
Insecticide sensitivity;;Boublik_2002_Protein.Eng_15_43
Back door hypothesis; enlarge back channel;Nachon_2008_Febs.J_275_2659
PaperMarcel_2000_J.Biol.Chem_275_11603
Stojan_2016_Chem.Biol.Interact_259_110
Boublik_2002_Protein.Eng_15_43
Nachon_2008_Febs.J_275_2659
NewsAPRIL-24-2008
Commentp.Trp121Ala
p.W121A Trp121Ala Catalytic anionic site. Mutation W83A in mature protein. Numbering in Boublik et al. 2002
Mutation W83A in mature protein. Numbering in Boublik et al. 2002
Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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