Y72N/Y124Q/W286A/F295L/F297V/Y337A p.Tyr72Asn/Tyr124Gln/Trp286Ala/Phe295Leu/Phe297Val/Tyr337Ala (Y103N/Y155Q/W317A/F326L/F328V/Y368A p.Tyr103Asn/Tyr124Gln/Trp317Ala/Phe326Leu/Phe328Val/Tyr368Ala in primary sequence with 31 amino-acids signal peptide) Acyl specificity;replacement of aromatic active center residues in human-ACHE by the corresponding residues in human-BCHE