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Mutation Report for: Y72N/Y124Q_human-ACHE

Name Class
Y72N/Y124Q_human-ACHEGene_locushuman-ACHE
Torpedo_number (3)
AA_ChangeY72N/Y124Q
Mode_of_mutationSite directed mutagenesis
ModificationAcyl specificity
SummaryAcyl specificity; replacement of aromatic active center residues in human-ACHE by the corresponding residues in human-BCHE;Kaplan_2001_Biochemistry_40_7433
PaperKaplan_2001_Biochemistry_40_7433
Kinetic_parameter (6)
Commentp.Y72N/Y124Q Tyr72Asn/Tyr124Gln (p.Y103N/Y155Q Tyr103Asn/Tyr155Gln in primary sequence with 31 amino-acids signal peptide) Acyl specificity; replacement of aromatic active center residues in human-ACHE by the corresponding residues in human-BCHE
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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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