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Inhibitor Report for: ZINC10109382-S0A-3WK4
Name
Class
ZINC10109382-S0A-3WK4
Type
Urea derivative
Cyclopropyl
Other_Name
S0A
ZINC10109382
Q27465193
Chemical_Nomenclature
1-[(1R)-1-cyclopropylethyl]-3-phenylurea
Formula
C12H16N2O
MW
204.27
Paper
Amano_2014_Bioorg.Med.Chem_22_2427
Structure
3WK4
Comment
not really a good inhibitor IC50: 7400 (nM) using PHOME as substrate
Gene_locus
human-EPHX2
CID
51473388
Family
Epoxide_hydrolase
InChIKey
VBBOGUVAPQGDSX-SECBINFHSA-N
CanonicalSMILES
CC(C1CC1)NC(=O)NC2=CC=CC=C2
InChI
InChI=1S/C12H16N2O/c1-9(10-7-8-10)13-12(15)14-11-5-3-2-4-6-11/h2-6,9-10H,7-8H2,1H3,(H2,13,14,15)/t9-/m1/s1
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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