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Gene_locus Report for: human-ABHD17A

Name Class
human-ABHD17ANameHomo sapiens (Human) Abhydrolase domain-containing protein FAM108A1, C19orf27 ABHD17A
SpeciesHomo sapiens
Organismman
Gene_nameFAM108A1
C19orf27
FLJ00008
ABHD17A
BlockX
FamilyABHD17-depalmitoylase
Database (14)
Paper (7)
CommentABHD17 proteins are protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization (Lin and Conibear 2015) They are probably themselves palmitoylated. ABHD17A, 17B, and 17C,are identified as the physiological PSD-95 (the most abundant postsynaptic density scaffolding protein) depalmitoylating enzymes in neurones (Yokoi et al.)
Proteinhuman-ABHD17A
Peptidehuman-ABHD17A
InhibitorPalmostatin-B
SubstrateDepalmitoylation-probe-2
Tree_nodeABHD17-depalmitoylase21681
Hydrolase_4241893
OldTremblQ5RGM9

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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