Gene_Locus Report

Biblio print

Add to basket

Go to basket

Tree Display

AceDB Schema

XML Display

Feedback

Gene_locus Report for: human-AFMID

Name Class
human-AFMIDNameHomo sapiens (Human) Kynurenine formamidase
SpeciesHomo sapiens
Organismhuman
Gene_nameAfmid
BlockH
FamilyKynurenine-formamidase
Database (9)
PaperLin_2018_Genome.Res_28_275
Bechtel_2007_BMC.Genomics_8_399
Gerhard_2004_Genome.Res_14_2121
Pabarcus_2002_Biochim.Biophys.Acta_1596_201
CommentCatalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites. Normal hepatocyte expresses high levels of AFMIDFL isoform, and tryptophan can be converted to NAD+ for PARPs to fix DNA damage
Proteinhuman-AFMID
Peptidehuman-AFMID
SubstrateN-formylkynurenine
Tree_nodeKynurenine-formamidase246291

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer