Type_inhibitor Report for: Alkaloid

Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom, produced by a large variety of organisms including bacteria, fungi, plants, and animals. The boundary between alkaloids and other nitrogen-containing natural compounds is not clear-cut.

Inhibitor	Main targeted enzyme families	Type

16-epi-Vellosimine	Hydroxynitrile_lyase	Alkaloid

18-carboxymethoxy-cleaviminium	Plant_carboxylesterase	Alkaloid \| Natural

8-Hydroxydihydrochelerythrine	ACHE	Alkaloid \| Benzodioxo \| Phenanthridinium

Atropine	ACHE	Alkaloid \| Drug \| Muscarinic antagonist \| Natural \| Not A/B H target \| Propionate

Berberine	ACHE \| BCHE	Alkaloid \| Benzodioxo \| Isoquinoline \| Natural \| Not A/B H target

Bis-galanthamine	ACHE	Alkaloid \| Alkyl linked bis-ligand \| Derivative of Galanthamine

CD-Bzl	BCHE	Alkaloid \| Derivative of Cinchonine \| Natural_modified \| Quinoline

Caffeine	Lipase_3 \| Pectinacetylesterase-Notum	Alkaloid \| Drug \| Natural \| Not A/B H target \| Purine

Canadine	ACHE \| BCHE \| Cholinesterase	Alkaloid \| Natural

Carltonine-A	BCHE	Alkaloid \| Natural

Carltonine-B	BCHE	Alkaloid \| Natural

Chelerythrine	ACHE	Alkaloid \| Benzodioxo \| Natural \| Not A/B H target \| Phenanthridinium

Cinchonidine	BCHE	Alkaloid \| Derivative of Cinchonine \| Natural \| Quinoline

Cinchonine	BCHE	Alkaloid \| Derivative of Cinchonine \| Natural \| Quinoline

Cocaine	BCHE	Alkaloid \| Benzoate \| Drug \| Natural \| Not A/B H target

Compound87	BCHE	Alkaloid \| Natural_modified

Cotinine	Pectinacetylesterase-Notum	Alkaloid \| Derivative of Nicotine \| Drug \| Natural \| Nicotinic agonist \| Not A/B H target \| Pyrrolidine

D-tubocurarine	ACHE	Alkaloid \| Drug \| Natural \| Neuromuscular Nondepolarizing Agents \| Not A/B H target

Desoxypeganine	ACHE \| BCHE	Alkaloid \| Natural \| Not A/B H target \| Quinazoline

Emetine	Hydrolase_RBBP9_YdeN	Alkaloid \| Drug \| Isoquinoline \| Natural \| Quinoline

Galanthamine	ACHE	Alkaloid \| Derivative of Galanthamine \| Drug \| Natural

Galanthaminium	ACHE	Alkaloid \| Derivative of Galanthamine \| Natural_modified

Gramine	ACHE \| BCHE	Alkaloid \| Indole \| Natural \| Not A/B H target

Harmine		Alkaloid \| Natural \| beta-carboline

HuperzineA	ACHE	Alkaloid \| Derivative of Huperzine \| Natural

HuperzineB	ACHE	Alkaloid \| Derivative of Huperzine \| Natural

Mahanimbine		Alkaloid \| Natural

Memogain	ACHE \| Carb_B_Chordata	Alkaloid \| Benzoate \| Derivative of Galanthamine \| Natural_modified

N-piperidinopropylgalanthamine	ACHE	Alkaloid \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Natural_modified \| Piperidine

N-saccharinohexylgalanthamine	ACHE	Alkaloid \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Natural_modified \| Sulfur Compound

Nicotine	ACHE \| BCHE \| Pectinacetylesterase-Notum	Alkaloid \| Derivative of Nicotine \| Drug \| Natural \| Nicotinic agonist \| Not A/B H target \| Pyrrolidine

Palmatine		Alkaloid \| Isoquinoline \| Natural \| Not A/B H target

Peganine	ACHE \| BCHE	Alkaloid \| Natural_modified \| Not A/B H target

Phthalimido-Galanthaminium-4d	ACHE	Alkaloid \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Isoindole \| Natural_modified \| Phthalimido

Phthalimido-Galanthaminium-8d	ACHE	Alkaloid \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Isoindole \| Natural_modified \| Phthalimido

Psilocybin	ACHE \| BCHE	Alkaloid \| Indole \| Natural \| Organophosphate

Sanguinarine		Alkaloid \| Benzodioxo \| Natural \| Not A/B H target \| Phenanthridinium

Sanguinine	ACHE	Alkaloid \| Derivative of Galanthamine \| Natural

Solanidine	BCHE	Alkaloid \| Natural \| Steroid

Solanine	BCHE	Alkaloid \| Carbohydrate \| Glycoside \| Natural

Thalictricavine	ACHE \| BCHE \| Cholinesterase	Alkaloid \| Natural

Theophylline	Pectinacetylesterase-Notum	Alkaloid \| Natural \| Not A/B H target

Vinblastine	Arylacetamide_deacetylase \| Carb_B_Chordata	Alkaloid

alpha-Chaconine	BCHE	Alkaloid \| Glycoside \| Natural

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

webmaster

Acknowledgements and disclaimer