Type Inhibitor

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Type_inhibitor Report for: Antioxidant

Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals and chain reactions that may damage the cells of organisms. Ellements of multi target drugs that are designed for example to inhibit cholinesterases and limit free radicals produced in the brain of patients suffering of Alzheimer disease

InhibitorMain targeted enzyme familiesTypeStructure
6F7Q-cpd11BCHE Antioxidant | Carboxamide | Inden | Metal ion chelator | Multitarget | Piperidine | Quinoline
6ZWE-Cpd3ACHE | BCHE Alkyl linked bis-ligand | Antioxidant | Benzodioxo | Multitarget
8U2-7AIX7AY-compound5iACHE | BCHE Alkyl linked bis-ligand | Antioxidant | Derivative of Capsaicin | Derivative of Huperzine | Multitarget | Quinoline
8U5-7AIW-compound5gACHE Alkyl linked bis-ligand | Antioxidant | Derivative of Capsaicin | Derivative of Huperzine | Multitarget | Quinoline
8UE-7AIV-compound5fACHE Alkyl linked bis-ligand | Antioxidant | Derivative of Capsaicin | Derivative of Huperzine | Multitarget | Quinoline
8UH-7AIS-compound5bACHE Alkyl linked bis-ligand | Antioxidant | Derivative of Capsaicin | Derivative of Huperzine | Multitarget | Quinoline
8UK-7AIT-compound5cACHE Alkyl linked bis-ligand | Antioxidant | Derivative of Capsaicin | Derivative of Huperzine | Multitarget | Quinoline
8UQ-7AIU-compound5dACHE Alkyl linked bis-ligand | Antioxidant | Derivative of Capsaicin | Derivative of Huperzine | Multitarget | Quinoline
Chlorotacrine-jugloneACHE Acridine | Alkyl linked bis-ligand | Antioxidant | Derivative of Tacrine | Multitarget | Naphthalen | anti-Abeta-aggregation
DFAH-12ACHE | BCHE Antioxidant | Derivative of Donepezil | Hydroxycinnamic-ester | Multitarget | Piperidine
Di-tert-butyl-4-Amino-2,3-cycloheptaquinoline-8cBCHE Antioxidant | Multitarget | Quinoline | tert-Butyl
Di-tert-butyl-phenol-octylamino-acridine-17dACHE Acridine | Alkyl linked bis-ligand | Antioxidant | Derivative of Tacrine | Multitarget | tert-Butyl
Di-tert-butyl-phenol-octylamino-cycloheptaquinolin-18dBCHE Alkyl linked bis-ligand | Antioxidant | Derivative of Tacrine | Multitarget | Quinoline | tert-Butyl
Donepezil-8-Hydroxyquinoline-2bBCHE Antioxidant | Derivative of Donepezil | Multitarget | Quinoline
Donepezil-Melatonin-4uACHE Alkyl linked bis-ligand | Antioxidant | Derivative of Donepezil | Derivative of Tryptamine | Indole | Multitarget
Donepezil-idebenone-cpd9BCHE Antioxidant | Derivative of Donepezil | Multitarget | anti-Abeta-aggregation
FluoropezilACHE Antioxidant | Derivative of Donepezil | Multitarget | Sulfur Compound
LipocrineACHE Alkyl linked bis-ligand | Antioxidant | Derivative of Tacrine | Multitarget | Sulfur Compound
Melatonin-alkylbenzylamine-Cpd5BCHE Alkyl linked bis-ligand | Antioxidant | Derivative of Tryptamine | Indole | Multitarget
MemoquinACHE Alkyl linked bis-ligand | Antioxidant | BACE1-inhibitor | Multitarget
Phenothiazine-Tacrine-1dCACHE Acridine | Alkyl linked bis-ligand | Antioxidant | Derivative of Tacrine | Multitarget | Phenothiazine | Sulfur Compound | anti-Abeta-aggregation
Pyranone-carbamate-cpd7pBCHE Antioxidant | Carbamate | Piperidine
Salicylamide-8-TacrineACHE | BCHE Alkyl linked bis-ligand | Antioxidant | Derivative of Tacrine | Multitarget | Salicylic
TFAH-tacrine-ferulic-acid-hybrid-10nBCHE Acrylate | Alkyl linked bis-ligand | Antioxidant | Derivative of Tacrine | Hydroxycinnamic-ester | Multitarget
Tacrine-Melatonin-Feruloyl-5cBCHE Acrylate | Alkyl linked bis-ligand | Antioxidant | Derivative of Tacrine | Derivative of Tryptamine | Feruloyl | Hydroxycinnamic-ester | Indole | Multitarget
Tacrine-Resveratrol-12ACHE Antioxidant | Derivative of Tacrine | Multitarget
Tacrine-Trolox-7uACHE Alkyl linked bis-ligand | Antioxidant | Carboxamide | Derivative of Tacrine | Multitarget
Tetracyclic-carbamate-ferulicacid-4a Alkyl linked bis-ligand | Antioxidant | Carbamate | Derivative of Evodiamine | Feruloyl | Isoquinoline | Natural_modified | Quinazoline

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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