Type_inhibitor Report for: beta-carboline

The prototype of a class of indole alkaloid compounds widespread in prokaryotes, plants and animals. Synthetically designed beta-carboline derivatives have recently been shown to have neuroprotective, cognitive enhancing, anti-cancer and antioxidant properties. GSK-3 kinase inhibitors

Inhibitor	Main targeted enzyme families	Type

6H14-(S)6	ACHE	Derivative of Tacrine \| Derivative of Valmerin \| GSK-3 kinase inhibitor \| Isoindole \| Multitarget \| Triazol \| Urea derivative \| beta-carboline

Dehydroevodiamine	ACHE	Derivative of Evodiamine \| Natural \| Natural_modified \| Pyridine \| beta-carboline

Evodiamine	BCHE	Derivative of Evodiamine \| Multitarget \| Natural \| Not A/B H target \| beta-carboline

Harmine		Alkaloid \| Natural \| beta-carboline

Methylene-blue-carboline-2	ACHE \| BCHE \| Cholinesterase	Drug \| Dye \| Multitarget \| Phenothiazine \| Sulfur Compound \| beta-carboline

ZLWH-23	ACHE	Carboxamide \| Cyclopropyl \| GSK-3 kinase inhibitor \| Multitarget \| Piperidine \| beta-carboline

ZTL-11	ACHE	Carboxamide \| Cyclopropyl \| GSK-3 kinase inhibitor \| Multitarget \| Triazol \| beta-carboline

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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