Type Inhibitor

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Type_inhibitor Report for: Derivative of Donepezil

Donepezil used in treatment of Alzheimer Disease, trademark is Aricept Reversible inhibitor of AChE but not of BChE. Used as a building block of new inhibitors and also multi-target drug candidates

InhibitorMain targeted enzyme familiesTypeStructure
5DYT-5hbBCHE Derivative of Donepezil | Naphthalen | Piperidine | Sulfonamide | Sulfur Compound
5DYW-5hfBCHE Derivative of Donepezil | Naphthalen | Piperidine | Sulfonamide | Sulfur Compound
5DYW-5hf-C11BCHE Derivative of Donepezil | Naphthalen | PET probe | Piperidine | Sulfonamide | Sulfur Compound
5DYW-5hf-FBCHE Derivative of Donepezil | PET probe | Piperidine | Sulfonamide | Sulfur Compound
5DYY-5hhBCHE Derivative of Donepezil | Naphthalen | Piperidine | Sulfonamide | Sulfur Compound
7QB4-Cpd2 Coumarin | Derivative of Donepezil | Monoamine-oxidase-inhibitor | Multitarget
Aricept~Donepezil~E2020ACHE Derivative of Donepezil | Drug | Inden | Piperidine
BYYT-25ACHE | BCHE | Cholinesterase Derivative of Donepezil | Derivative of Rivastigmine | Inden
C7653ACHE Derivative of Donepezil | Piperidine
CHEMBL4293015 Alkyl linked bis-ligand | Derivative of Donepezil | Indole | Piperidine
DFAH-12ACHE | BCHE Antioxidant | Derivative of Donepezil | Hydroxycinnamic-ester | Multitarget | Piperidine
DonecoprideACHE 5-HT-receptor-ligand | Derivative of Donepezil | Multitarget | Piperidine
Donepezil-8-Hydroxyquinoline-2bBCHE Antioxidant | Derivative of Donepezil | Multitarget
Donepezil-Melatonin-4u Antioxidant | Derivative of Donepezil | Derivative of Tryptamine | Multitarget
Donepezil-derivative-DZ0ACHE Derivative of Donepezil | Inden | Piperidine
Donepezil-derivative-DZ7ACHE Derivative of Donepezil | Inden | Piperidine
Donepezil-idebenone-cpd9BCHE Antioxidant | Derivative of Donepezil | Multitarget | anti-Abeta-aggregation
FluoropezilACHE Antioxidant | Derivative of Donepezil | Multitarget | Sulfur Compound
IcopezilACHE Derivative of Donepezil | Piperidine
MC1420ACHE Carboxamide | Derivative of Donepezil
Mebbpp Derivative of Donepezil | Multitarget | Piperidine | Sulfur Compound
SelenepezilACHE Derivative of Donepezil | Organoselenium | Piperidine | Thiol-reactive
Sigma1R-ACHE-6aACHE 5-HT-receptor-ligand | Derivative of Donepezil | Multitarget | Piperidine | Sigma1R
Sigma1R-ACHE-6bACHE 5-HT-receptor-ligand | Derivative of Donepezil | Multitarget | Piperidine | Sigma1R
TAK-147ACHE Derivative of Donepezil | Piperidine | Transition state analogue
Tacrine-Donepezil-hybrid3ACHE Derivative of Donepezil | Derivative of Tacrine
ZINC11709541ACHE Derivative of Donepezil | Trifluoro
ZINC11996936ACHE Derivative of Donepezil | Trifluoro

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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