Type Inhibitor

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Type_inhibitor Report for: Lipase inhibitor

Lipase inhibitors are substances used to reduce the activity of lipases found in the intestine. Lipases are secreted by the pancreas when fat is present. The primary role of lipase inhibitors is to decrease the gastrointestinal absorption of fats

InhibitorMain targeted enzyme familiesTypeStructure
3-Cholesteryl-N-butylcarbamateCholesterol_esterase Carbamate | Lipase inhibitor | Steroid
3-Cholesteryl-N-octylcarbamateCholesterol_esterase Carbamate | Lipase inhibitor | Steroid
C11Y4-phosphonateAcidic_Lipase | Cutinase Lipase inhibitor | Organophosphate
C12-myristoyl-MAG-like-phosphonateCarbLipBact_2 Analogue of substrate | Azido | Lipase inhibitor | Organophosphate | pNP
C14-palmitoyl-MAG-like-phosphonateCarbLipBact_2 Analogue of substrate | Azido | Lipase inhibitor | Organophosphate | pNP
C16-stearoyl-MAG-like-phosphonateCarbLipBact_2 Analogue of substrate | Azido | Lipase inhibitor | Organophosphate | pNP
C18-octadecyl-MAG-like-phosphonateMonoglyceridelipase_lysophospholip Analogue of substrate | Azido | Lipase inhibitor | Organophosphate | pNP
C4-C4-SN3-tributyrin-phosphonateHormone-sensitive_lipase_like Lipase inhibitor | Organophosphate
C6-C4-Sn3-phosphinateHormone-sensitive_lipase_like Lipase inhibitor | Organophosphate
C8-C4-Sn3-phosphinateHormone-sensitive_lipase_like Lipase inhibitor | Organophosphate
CetilistatPancreatic_lipase Lipase inhibitor
Cpd17-Pyrrolidine-THL-derivativeCutinase Lipase inhibitor | Oxooxetan | Pyrrolidine
CyC-17A85-Mycolyl-transferase | Carbon-carbon_bond_hydrolase | Cutinase | Hormone-sensitive_lipase_like | Thioesterase Cyclic OP | Lipase inhibitor | Organophosphate
CyC-17-openA85-Mycolyl-transferase Cyclic OP open | Lipase inhibitor | Organophosphate
CyC-31Carbon-carbon_bond_hydrolase Cyclic OP | Lipase inhibitor | Organophosphate
CyC-31-openCarbon-carbon_bond_hydrolase Cyclic OP | Cyclic OP open | Lipase inhibitor | Organophosphate
CyC-31yneCarbon-carbon_bond_hydrolase Alkyne | Cyclic OP | Lipase inhibitor | Organophosphate
CyC-32Carbon-carbon_bond_hydrolase Cyclic OP | Lipase inhibitor | Organophosphate
CyC-32yneCarbon-carbon_bond_hydrolase Alkyne | Cyclic OP | Lipase inhibitor | Organophosphate
CyC-7betaA85-Mycolyl-transferase Cyclic OP | Lipase inhibitor | Organophosphate
CyC-7beta-openA85-Mycolyl-transferase Cyclic OP open | Lipase inhibitor | Organophosphate
CyC-8betaA85-Mycolyl-transferase Cyclic OP | Lipase inhibitor | Organophosphate
CyC-8beta-openA85-Mycolyl-transferase Cyclic OP open | Lipase inhibitor | Organophosphate
Cyclipostin-PCutinase | Hormone-sensitive_lipase_like | Monoglyceridelipase_lysophospholip Cyclic OP | Lipase inhibitor | Natural | Organophosphate
Cyclophostin-enolphosphonateCutinase | Monoglyceridelipase_lysophospholip Cyclic OP | Lipase inhibitor | Organophosphate
DBOXAcidic_Lipase Benzofuran | Lipase inhibitor | Oxadiazol | Oxadiazolone
DSFAcidic_Lipase | LYsophospholipase_carboxylesterase Lipase inhibitor | NTE inhibitor | Not A/B H target | Sulfonyl | Sulfur Compound
EZ120A85-Mycolyl-transferase Lipase inhibitor | Oxooxetan
EZ120PA85-Mycolyl-transferase Alkyne | Lipase inhibitor | Oxooxetan
EsterastinAcidic_Lipase | Pancreatic_lipase Lipase inhibitor | Natural | Oxooxetan
L-Isoleucine-OrlistatLipase_3 Lipase inhibitor | Oxooxetan
Lalistat-16_AlphaBeta_hydrolase | Acidic_Lipase | Cutinase | Hormone-sensitive_lipase_like | Monoglyceridelipase_lysophospholip Lipase inhibitor | Piperidine | Sulfur Compound | Thiadiazol
Lalistat-26_AlphaBeta_hydrolase | Acidic_Lipase | Cutinase | Hormone-sensitive_lipase_like | Monoglyceridelipase_lysophospholip Lipase inhibitor | Piperidine | Sulfur Compound | Thiadiazol
Lalistat-alkyne-probe Alkyne | Lipase inhibitor | Piperidine | Sulfur Compound | Thiadiazol
LipstatinPancreatic_lipase Lipase inhibitor | Natural | Oxooxetan
MPOXAcidic_Lipase Lipase inhibitor | Oxadiazol | Oxadiazolone
MetoxadiazoneAcidic_Lipase Lipase inhibitor | Oxadiazol | Oxadiazolone
MmPPOXAcidic_Lipase Lipase inhibitor | Oxadiazol | Oxadiazolone | Phenoxyphenyl
MpPPOXAcidic_Lipase Lipase inhibitor | Oxadiazol | Oxadiazolone | Phenoxyphenyl
Myricitrin-5-methyl-etherAcidic_Lipase Flavonoid | Lipase inhibitor
N-Hexylphosphonate-Ethyl-EsterCanar_LipB | Cutinase | Hormone-sensitive_lipase_like | Lipase_3 Lipase inhibitor | Organophosphate
O-3841Lipase_3 Lipase inhibitor | Organophosphate
O-7460Lipase_3 Analogue of substrate | Lipase inhibitor | Organophosphate | Triacylglycerol
OrlistatA85-Mycolyl-transferase | ABHD16 | ABHD6-Lip | Acidic_Lipase | AlphaBeta_hydrolase | Bacterial_lip_FamI.6 | Carb_B_Chordata | Cutinase | Hormone-sensitive_lipase_like | Lipase_3 | Monoglyceridelipase_lysophospholip | PE-PPE | Pancreatic_lipase | Plasmodium_subtelomeric_PST-A | Thioesterase Lipase inhibitor | Oxooxetan
Sal-A-alkyneABHD13-BEM46 | ABHD17-depalmitoylase | Duf_676 | PGAP1 | Plasmodium_subtelomeric_PST-A ABPP-Probe | Alkyne | Cyclic OP | Lipase inhibitor | Organophosphate
Salinipostin-AABHD13-BEM46 | ABHD17-depalmitoylase | Duf_676 | PGAP1 | Plasmodium_subtelomeric_PST-A Cyclic OP | Lipase inhibitor | Natural | Organophosphate
THL-10dA85-Mycolyl-transferase Benzyloxycarbonyl | Lipase inhibitor | Oxooxetan
Tetrahydrolipstatin-alkyne Alkyne | Lipase inhibitor | Oxooxetan
Vibralactone Lactone | Lipase inhibitor | Natural
bis-benzene-sulfonamideCarb_B_Chordata | Carboxylesterase Lipase inhibitor | Sulfonamide | Sulfur Compound
di-O-octylglycero-O-(p-nitrophenyl)-n-hexyl-phosphonateBacterial_lip_FamI.2 | Lipase_3 Analogue of substrate | Lipase inhibitor | Organophosphate | Triacylglycerol | pNP
l,2-Dioctylcarbamoylglycero-3-O-p-nitrophenyloctylphosphonateBacterial_lip_FamI.6 | Cutinase Analogue of substrate | Lipase inhibitor | Organophosphate | Triacylglycerol | pNP

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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