Type Inhibitor

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Type_inhibitor Report for: Organophosphate

Comment

Organophosphates (also known as phosphate esters OP) are a class of organophosphorus compounds with the general structure O=P(OR)3. They can be considered as esters of phosphoric acid. Here we consider only those compounds that interact with alpha/beta hydrolases mostly as inhibitors (insecticides, nerve agents etc...). As the number of compounds increases in the database you can choose to select subsets such as: Chemical Warfare Agent or more precisely: Nerve Agent G-series, Nerve Agent V-series, Derivative of Sarin, Derivative of Soman, Surrogate OP, Organothiophosphate, Phosphonylatedoxime, or pesticides (including compounds not OP): Herbicide, Insecticide, Anthelmintic, or investigational compounds: Cyclic OP, ABPP-Probe, Flu-OP. You can also search another category of compounds in the list: Types of inhibitors

Inhibitor nameFormulaStructure
(Rc,RpSp)-3C9H12ClO3P
217-AOC8H20NO3PS
4-methylumbelliferyl-hexylphosphonateC17H23O5P
6RKY-K7KC17H23N2O4P
A-230-Nerve-agentC7H16FN2OP
A-232-Nerve-agentC7H16FN2O2P
A-234-Nerve-agentC8H18FN2O2P
ABP-C6C15H23N4O5P
AcephateC4H10NO3PS
ArM-Rhubidium-cofactor-8C50H41ClN4O7PRu
ArminC10H14NO5P
AzamethiphosC9H10ClN2O5PS
Azinphos-EthylC11H16N3O3PS2
Azinphos-MethylC10H12N3O3PS2
B4-4NHPC16H26NO5P
BCPC17H35N2O7P
BIMPC8H20O5P2
BNPPC12H9N2O8P
BPMPC14H32O5P2
BenoxafosC12H14Cl2NO3PS2
BensulideC14H24NO4PS3
BomylC9H15O8P
BromophosC8H8BrCl2O3PS
ButoxyhexylphosphonateC10H23O3P
Butylphosphonic-acidC4H11O3P
C11Y4-phosphonateC15H33O2P
C12-myristoyl-MAG-like-phosphonateC15H33N3O3P+
C14-palmitoyl-MAG-like-phosphonateC17H37N3O3P+
C16-stearoyl-MAG-like-phosphonateC19H41N3O3P+
C18-octadecyl-MAG-like-phosphonateC21H44N3O2P+2
C4-C4-SN3-tributyrin-phosphonateC14H31O5P
C6-C4-Sn3-phosphinateC18H39O5P
C8-C4-Sn3-phosphinateC19H41O5P
CBDPC14H13O4P
CGA-134-735C10H17O5P
CGA-134-736C8H13O5P
CHMP-S-ethylC10H21O2PS
CHMP-S-methylC9H19O2PS
CHMP-thiocholineC13H29NO2PS
CMP-DDAOC22H24Cl2NO4P
CMP-MeCyCC18H20NO5P
CadusafosC10H23O2PS2
CarbophenothionC11H16ClO2PS3
Chinese-VXC11H26NO2PS
ChlorethoxyfosC6H11Cl4O3PS
ChlorfenvinphosC12H14Cl3O4P
ChlormephosC5H12ClO2PS2
ChlorphoximC12H14ClN2O3PS
ChlorpyrifosC9H11Cl3NO3PS
Chlorpyrifos-methyl-oxonC7H7Cl3NO4P
Chlorpyrifos-oxonC9H11Cl3NO4P
ChlorthionC8H9ClNO5PS
CinnamoylphosphoramideC11H14NO5P
CoraloxC14H16ClO6P
CoumaphosC14H16ClO5PS
Coumarinyl-ethyl-p-trifluoroacetamidophenylmethylphosphonateC21H19F3NO6P
CoumithoateC17H21O5PS
CrotoxyphosC14H19O6P
CrotylsarinC5H10FO2P
CruformateC12H19ClNO3P
CyC-17C23H43O6P
CyC-31
CyC-7betaC19H35O5P
CyC-8betaC21H39O5P
CyanofenphosC15H14NO2PS
CyanophosC9H10NO3PS
Cyclipostin
Cyclipostin-PC23H41O6P
CyclophostinC8H11O6P
Cyclophostin-enolphosphonate
CyclosarinC7H14FO2P
CythioateC8H12NO5PS2
DEP-2PAMC11H18N2O4P+
DEP-4PAMC11H18N2O4P+
DEPQC14H19NO4P+
DEUPC13H15O6P
DFPC6H14FO3P
DMBMP-thiocholineC12H29NO2PS+
DOTA-(amide)4-(EG)n-tetraphosphonateC104H172N16O40P4
DPDCVPC12H23Cl2O4P
DPPFC12H10FOP
DemetonC8H19O3PS2
DialiforC14H17ClNO4PS2
Dialifor-oxonC14H17ClNO5PS
DiazinonC12H21N2O3PS
Diazinon-oxonC12H21N2O4P
Dibutyl-dichlorovinyl-phosphate~DBVPC10H19Cl2O4P
DichlofenthionC10H13Cl2O3PS
DichlorvosC4H7Cl2O4P
DicrotophosC8H16NO5P
DiethyltabunC8H17N2O2P
Diisopropyl-amitonC12H28NO3PS
Diisopropyl-phenyl_phosphateC12H19O4P
DimefoxC4H12FN2OP
DimethoateC5H12NO3PS2
Dimethyl-phosphorochloridateC2H6ClO3P
Dioctyl-dichlorovinyl-phosphate~DOVPC18H35Cl2O4P
DioxathionC12H26O6P2S4
Diphenyl-allylphosphonateC15H15O3P
Diphenyl-chlorophosphateC12H10ClO3P
Diphenyl-phosphateC12H11O4P
DisulfotonC8H19O2PS3
Disyston-sulfoxideC8H19O3PS3
EA-3148C12H26NO2PS
EDAMPC11H26NO3PS
EDMMC7H18NO2PS
EHDPPC20H27O4P
EMP-DDAOC18H18Cl2NO4P
EMP-MeCyCC14H14NO5P
EMP-TMB4C19H27Cl2N403P
EMP-ToxogoninC18H25Cl2N4O4P
EMPAC3H9O3P
EMPCC13H15O5P
EOPFC10H22FO2P
EPNC14H14NO4PS
EPN-oxonC14H14NO5P
EPOC11H17O5P
EPPATC8H12NO2PS
EchothiophateC9H23INO3PS
EthephonC2H6ClO3P
EthionC9H22O4P2S4
Ethyl-bromophosC10H12BrCl2O3PS
EthylchlorthionC10H13ClNO5PS
EthylsarinC3H8FO2P
FP-AzidoC14H28FN4O3P
FP-BiotinC27H50FN4O5PS
FP-DesthiobiotinC22H43FN3O4P
FP-TAMRAC37H47FN3O6P
FamphurC10H16NO5PS2
FenamiphosC13H22NO3PS
FenchlorphosC8H8Cl3O3PS
FenitrothionC9H12NO5PS
FensulfothionC11H17O4PS2
FenthionC10H15O3PS2
Fenthion-oxonC10H15O4PS
Fluorophosphonate-nocardicin-GC19H21FN3O6P
FlupyrazofosC14H16F3N2O3PS
FonofosC10H15OPS2
FormothionC6H12NO4PS2
FosthiazateC9H18NO3PS2
FosthietanC6H12NO3PS2
GVC6H16FN2O2P
GuanitoxinC7H17N4O4P
HDFPC18H38FO2P
HaloxonC15H16Cl3O5P
HeptenophosC9H12ClO4P
Hexyl(2R)-2-methyl-3-phenylpropoxyphosphinic-acidC16H27O3P
Hexyl(2S)-2-methyl-3-phenylpropoxyphosphinic-acidC16H27O3P
IBMPFC5H12FO2P
IDFPC15H32FO2P
IDFPenC15H30FO2P
IMP-DDAOC20H22Cl2NO4P
IMP-MeCyCC15H16NO5P
IMP-pNPC10H14NO5P
IMP-pNP-FC10H13FNO5P
IPG-PhosphonateC12H23O5P
IPTPC27H33O4P
Iso-OMPAC12H32N4O3P2
IsocarbophosC11H16NO4PS
IsochlorthionC8H9ClNO5PS
IsofenphosC14H14NO4PS
IsomalathionC10H19O6PS2
IsoparathionC10H14NO5PS
IsoxathionC13H16NO4PS
KitazinC11H17O3PS
LI5-1YCDC7H12O6P
LeptophosC13H10BrCl2O2PS
Lys-phospho-isoindolineC30H36N5O6P
M4-4NHPC13H20NO5P
MEPQC13H17INO2P
MFPChC6H16FNO2P+
MFPbetaChC7H18FNO2P+
MFPhChC7H18FNO2P+
MHHC7H17O3P
MSPIC5H9N2O2PS
MUPC12H27O3P
MaglipanC20H42FO2P364.52
MalaoxonC10H19O7PS
MalathionC10H19O6PS2
MecarbamC10H20NO5PS2
Menthyl-hexyl-phosphonateC16H33O3P
MethamidophosC2H8NO2PS
MethidathionC6H11N2O4PS3
Methyl-DEUPC14H17O6P
Methyl-arachidonyl-fluorophosphonateC21H36FO2P
Methyl-demetonC12H30O6P2S4
Methyl-gamma-linolenyl-fluorophosphonateC19H34FO2P
MethylchlorpyrifosC7H7Cl3NO3PS
MethylparaoxonC8H10NO6P
MethylparathionC8H10NO5PS
MethylsarinC2H6FO2P
MethyltrithionC9H12ClO2PS3
MevinphosC7H13O6P
MipafoxC6H16FN2OP
MocapC8H19O2PS2
MonocrotophosC7H14NO5P
N-Hexylphosphonate-Ethyl-EsterC8H19O3P
NBD-AE-MPFC9H10FN4O5P
NBD-AP-MPFC12H16FN4O5P
NBD-CPC57H87N6O10P
NBD-HE-HPC26H35N6O9P
NBD-P-MPFC12H15FN3O5P
NBD-TGC66H114N6O12P
NCMPC13H18NO5P
NEDPAC10H15N2O5P
NEMPC9H12NO5P
NEMP-FC9H11FNO5P
NXCC17H30ClN2O3PPt-
NaftalofosC16H16NO6P
NaledC4H7Br2Cl2O4P
Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonateC25H31N4O6PS
Novichok-5~A-230C3H4Cl2F2NO3P
Novichok-5~A-232C4H6Cl2F2NO3P
Novichok-7~A-234C5H8Cl2F2NO3P
O-3841C23H46FO4P
O-7460C25H48FO5P
O-hexyl-O-2,5-dichlorophenyl-phosphoramidateC12H18Cl2NO3P
OBDPOC15H24O3P
OCPC29H59N2O7P
OMPAC8H24N4O3P2
Octyl-diphenyl-phosphateC20H27O4P
OmethoateC5H12NO4PS
PIMPC12H14NO5P
PMP-DDAOC22H26Cl2NO4P
PMP-MeCyCC18H22NO5P
PSKC7H15O4P
PSXC7H17O5P
ParaoxonC10H14NO6P
ParathionC10H14NO5PS
Parathion-SC10H14NO5PS
PhXC16H28NO2PS
PhenthoateC12H17O4PS2
Phenyl-di-n-pentylphosphinateC16H27O2P
Phenyl-saligenin-phosphate~PSPC13H11O4P
PhenylPhosphonateAzidoProbe3C7H13FN3O4P
PhenylPhosphonateAzidoProbe4C13H17N4O7P
PhenylPhosphonateAzidoProbe5C13H17F5N3O5PS
PhorateC7H17O2PS3
PhosacetimC14H13Cl2N2O2PS
PhosaloneC12H15ClNO4PS2
PhosmetC11H12NO4PS2
PhosmetoxonC11H12NO5PS
PhosphamidonC10H19ClNO5P
Phosphonate-MSWC13H20NO5P
Phosphopantetheine-linked-pimeloyl-methyl-esterC19H35N2O10PS
Phosphopentaketide-11C11H23O6P
PhoximC12H15N2O3PS
Pirimiphos-methylC9H16N3O3PS
PrDChVPC8H15Cl2O4P
ProfenofosC11H15BrClO3PS
PropaphosC13H21O4PS
PropetamphosC10H20NO4PS
ProthiofosC11H15Cl2O2PS2
PsilocybinC12H17N2O4P
PyraclofosC14H18ClN2O3PS
PyrazophosC14H20N3O5PS
PyrazothionC8H15N2O3PS
PyrazoxonC8H15N2O4P
PyridaphenthionC14H17N2O4PS
QuinalphosC12H15N2O3PS
RabonC10H9Cl4O4P
Rh-pNPC39H55ClN3O5PRh
Ru-NHC-1C40H49Cl2N3O6PRu
Ru-NHC-3C43H55Cl2N3O6PRu
Russian-VXC11H26NO2PS
S9BC26H41N4O5PS
SCHEMBL177496C21H36FO3P
SCHEMBL3294100C11H17O4P
SXCC15H26BrO3PPdS2+2
Sal-A-alkyneC25H41O6P
Salinipostin-AC25H45O6P
SalioxonC8H9O4P
SalithionC8H9O3PS
SarinC4H10FO2P
SayphosC6H12N5O2PS2
SomanC7H16FO2P
SulfotepC8H20O5P2S2
SulprofosC12H19O2PS3
SystemoxC16H38O6P2S4
TEMPC8H9Cl3NO3P
TMPC3H9O3PS
TMPDC3H9O2PS2
TMPSC3H9O3PS
TPHPC18H15O4P
TSA-Phenoxy-Acetoxy-ButaneC11H16ClO3P
TabunC5H11N2O2P
TebupirimfosC13H23N2O3PS
TemephosC16H20O6P2S3
TerbufosC9H21O2PS3
TetraethylpyrophosphateC8H20O7P2
ThiometonC6H15O2PS3
Tolclofos-methylC9H11Cl2O3PS
Tri-M-cresyl-phosphateC21H21O4P
Tri-o-cresylphosphateC21H21O4P
TriazophosC12H16N3O3PS
TribufosC12H27OPS3
Trichlorfon~MetrifonateC4H8Cl3O4P
UlosantoinC5H9N2O5P
VEC10H24NO2PS
VGC10H24NO3PS
VMC9H22NO2PS
VSC12H28NO2PS
VXC11H26NO2PS
VX-BiotinC30H60N4O4PS2+
VXSC9H12NO6P
VamidothionC8H18NO4PS2
alkyne-PEG-FPC15H28FO6P
dMUPC12H13O6P
di-O-octylglycero-O-(p-nitrophenyl)-n-hexyl-phosphonateC31H56NO7P
diBu-PFPC11H19F6O4P
diEt-PFPC7H11F6O4P
i-ButylsarinC5H12FO2P
iso-PentylsarinC6H14FO2P
l,2-Dioctylcarbamoylglycero-3-O-p-nitrophenyloctylphosphonateC35H62N3O9P
mitoFPC30H40F2O2P2
n-ButylsarinC5H12FO2P
n-PentylsarinC6H14FO2P
n-PropylsarinC4H10FO2P
neo-PentylsarinC6H14FO2P
sec-PentylsarinC6H14FO2P
thio-NADC21H27N7O13P2S

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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