Type Inhibitor

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Type_inhibitor Report for: Sulfonyl

Sulfonyl groups with the general formula RS(=O)2R, where there are two double bonds between the sulfur and oxygen. Sulfonamide are included in another. Building block for many inhibitors of enzymes

InhibitorMain targeted enzyme familiesTypeStructure
1-dodecanesulfonyl-chlorideFungal_carboxylesterase_lipase Sulfonyl | Sulfur Compound
1-hexadecanesulfonyl-chlorideBacterial_lip_FamI.5 | Fungal_carboxylesterase_lipase | Hormone-sensitive_lipase_like | Palmitoyl-protein_thioesterase Sulfonyl | Sulfur Compound
34NEpoxide_hydrolase Cyanide | Sulfonyl | Sulfur Compound
3TPDPP4N_Peptidase_S9 Oxadiazol | Pyrrolidine | Sulfonyl | Sulfur Compound
5ALH-4UAEpoxide_hydrolase Carboxamide | Piperidine | Sulfonamide | Sulfonyl | Sulfur Compound
5ALZ-XQ9Epoxide_hydrolase Adamantyl | Piperidine | Sulfonamide | Sulfonyl | Sulfur Compound | Urea derivative
64DMonoglyceridelipase_lysophospholip PET probe | Piperidine | Sulfonyl | Sulfur Compound
AEBSF5_AlphaBeta_hydrolase | DPP4N_Peptidase_S9 | S9N_PREPL_Peptidase_S9 | Tiancimycin-TnmK-Tripeptidase-HIP Sulfonyl | Sulfur Compound
AM3506Monoglyceridelipase_lysophospholip FAAH inhibitor | Sulfonyl | Sulfur Compound
Benzenesulfonyl-fluorideACHE Sulfonyl | Sulfur Compound
CHEMBL3087813ACHE Benzenesulfonamide | Sulfonamide | Sulfonyl | Sulfur Compound
CHEMBL469792Epoxide_hydrolase Carboxamide | Piperidine | Sulfonyl | Sulfur Compound
DSFAcidic_Lipase | LYsophospholipase_carboxylesterase Lipase inhibitor | NTE inhibitor | Not A/B H target | Sulfonyl | Sulfur Compound
Flouroolefin-2DPP4N_Peptidase_S9 Cyclopropyl | Oxadiazol | Sulfonyl | Sulfur Compound
HDSFPalmitoyl-protein_thioesterase Sulfonyl | Sulfur Compound
JCP678A85-EsteraseD-FGH Carbamate | Sulfonyl | Sulfur Compound
LIPG-inhib-Compound32Lipoprotein_Lipase Benzothiazol | Cyclopropyl | Pyridine | Sulfonyl | Sulfur Compound
LK864Epoxide_hydrolase Azaspiro | Sulfonyl | Sulfur Compound | Trifluoro | Urea derivative
MSFACHE Sulfonyl | Sulfur Compound
OSF NTE inhibitor | Not A/B H target | Sulfonyl | Sulfur Compound
OTFPdOHSO2Juvenile_hormone_esterase Halo ketone | Sulfonyl | Sulfur Compound | Trifluoro
P9-benzothiadiazoleHaloalkane_dehalogenase-HLD2 Fluorescent Probe | Sulfonyl | Sulfur Compound | Thiadiazol
PMSFABHD10 | ACHE | Acetyl-esterase_deacetylase | Acetyl_esterase | BCHE | Bacterial_lip_FamI.1 | Bacterial_lip_FamI.5 | BioH | CarbLipBact_1 | CarbLipBact_2 | Cocaine_esterase | Cutinase | DPP4N_Peptidase_S9 | Dienelactone_hydrolase | Duf_1100-S | FAE-Bacterial-promiscuous | GTSAGmotif | Hormone-sensitive_lipase_like | Kynurenine-formamidase | LYsophospholipase_carboxylesterase | Lactobacillus_peptidase | Monoglyceridelipase_lysophospholip | PE-PPE | Pectinacetylesterase-Notum | Peptidase_S15 | Peptidase_S37 | PolyAspartate-hydrolase | Polyesterase-lipase-cutinase | RsbQ-like | S9N_PREPL_Peptidase_S9 | Thioesterase Sulfonyl | Sulfur Compound
Piperidine-fused-benzimidazole-25DPP4N_Peptidase_S9 Benzimidazole | Imidazole | Piperidine | Sulfonyl | Sulfur Compound | Trifluoro
SCHEMBL15589912Lipoprotein_Lipase Benzothiazol | Morpholine | Oxadiazol | Sulfonyl | Sulfur Compound

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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