Type Inhibitor

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Type_inhibitor Report for: anti-tau-aggregation

Comment

Accumulation of abnormal tau aggregates in neuron is an important pathological signature in multiple neurodegenerative disorders. Not an alpha/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compounds

Inhibitor nameFormulaStructure
Ass-IN-10C29H38N2O
Methylene-blueC16H18N3S

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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