Type Reactivator

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Type_reactivator Report for: Oxime

Comment

Componds like RR'C=NOH, where R is an organic side-chain and R' may be hydrogen, forming an aldoxime, or another organic group, forming a ketoxime. Oxime compounds can reactivate OP inhibited cholinesterases by attaching to phosphorus, forming an oxime-phosphonate, which then splits away from the acetylcholinesterase molecule

Reactivator nameFormulaStructure
15FC15H14Cl3N2O
2-PAMC7H9N2O
2BIM-7C15H26N6O2
3-PAMC7H9N2O
4-PAMC7H9N2O
4-methyl-3-nitrobenzamido-pentyl-PAM-7dC19H23N4O4
7-MEOTA-4-pyridinealdoximeC25H33BrN4O2
7P1N-4J1C22H33N5O8
7P1P-4IXC21H31N5O8
BDB-106C14H20N6O2
BDB-108C16H18Br2N4O2
BDB-110C14H22N6O2
BI-6C16H18N4O2
Benzyl-P2AC13H13ClN2O
C35-CVZC33H44N6O6
CBIOC15H17ClN3O
Cl-HINC8H5ClN2O2
DAMC4H7NO2
DMB-4C14H16N4O2+2
GM415C22H29N3O4
GM508C30H39N4O4
HGG-12C20H19I2N3O3
HGG-21C15H17I2N3O3
HGG-42C20H25I2N3O3
HGG-52C19H25Cl2N3O3
HI-6C14H16Cl2N4O3
HLo-7C15H17I2N5O4
HS-3C14H16Cl2N4O3
HS-6C14H16Cl2N4O3
ICD-467C11H19ClN4O4
JR585C16H25N3O2
JR595C14H21N3O3
K005C15H18N4O2
K027C15H18N4O2
K027-Cl2C15H16Cl2N4O2+
K033C16H20N4O2
K048C16H20N4O2
K074C14H16N4O2+2
K075C16H18N4O2
K117C16H20N4O3+2
K127C16H20Br2N4O3
K131C19H21Br2N3O
K1374C26H28N4O22+
K1375C17H22N4O32+
K142C19H21Br2N3O
K153C15H19Br2N3O
K156C14H17N3O
K203C16H18N4O2
K206C16H17N4O2
K454C20H21Br2N3O
K456C16H19Br2N3O2
K458C15H19Br2N5O2
K727C24H22Br2N4O2
K733C22H24Br2N3O3
K869C16H19Br2ClN4O2
LG-703C13H24N6O4
LLNL-02C15H21N3O2
MF5C14H10F5N2O+
MINAC3H5NO2
MMB-4C13H14Br2N4O2
Ortho-7C19H26N4O2-2+
Oxime-20C23H25N2O3+
P2s~contrathionC7H9IN2O
PAMC6H6N2O
PCM-0211088C14H14N2O2
PCM-0211338C14H14N4O2
PCM-0211955C7H6BrNO2
PCM-0212399C6H7N3O2
Phenyltetrahydroisoquinoline-Pyridinaldoxime-1bC27H31N3O4
Phenyltetrahydroisoquinoline-Pyridinaldoxime-1cC28H33N3O4
Q8-Quinuclidine-3-oximeC14H18Br2N2O
R665C17H22I2N4O4
RM048C15H23N3O3
RS170BC13H16N5O2
RS194BC10H19N3O2
TAB2OHC10H15ClN2O2
Tacrine-pyridinealdoxime-1C23H27N4O2
Tacrine-pyridinealdoxime-2C23H25ClN4O2
ToxogoninC14H16Cl2N4O3
Triazole-annulated-oxime-14AC17H19N7O2
Triazole-annulated-oxime-2AC19H22N5O
Triazole-annulated-oxime-3AC19H22N7O2
TrimedoximeC15H18Br2N4O2
Triple-binding-oxime-IIIC18H21N7O2
Triple-binding-oxime-III-RC18H22N8O2
Tryptoline-hydroxy-pyridinaldoxime-3C21H24N4O2
Tryptoline-hydroxy-pyridinaldoxime-4C22H26N4O2
pro-2PAMC7H11ClN2O

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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