Type Substrate

Tree Display

AceDB Schema

XML Display

Feedback

Type_substrate Report for: Benzodiazepin

Comment

Benzodiazepine is the fusion of a benzene ring and a diazepine ring. Drugs which lower brain activity (diazepam Valium) enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor. Not A/B hydrolase targets but some prodrugs are substrates of esterases

Substrate nameFormulaStructure
IomazenilC15H14IN3O3
RemimazolamC21H19BrN4O2
W22-methyl-esterC13H16N2O3

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer