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Type_substrate Report for: Natural

Substrates or inhibitors found in nature. Toxins are harmful substances produced within living cells or organisms
See also this moiety in type of inhibitors: Natural

SubstrateMain targeted enzyme familiesTypeStructure
1,3,6-TrigalloylglucoseTannase | Tannase_Bact Derivative of Gallate | Natural | Polyphenol
1,5-Seco-vibralactoneHormone-sensitive_lipase_like Lactone | Natural
1-Oleoyl-2-arachidonoyl-sn-glycerolLipase_3 Acyl-Glycerol | Natural
1-Stearoyl-2-arachidonoylglycerolLipase_3 Acyl-Glycerol | Natural
15-Hete-G Acyl-Glycerol | Cannabinoid-Receptor-ligand | Natural
2-ArachidonylglycerolABHD12-PHARC | ABHD6-Lip | Carb_B_Chordata | Monoglyceridelipase_lysophospholip | abh_upf0017 Acyl-Glycerol | Cannabinoid-Receptor-ligand | Natural
2-Heptyl-3-hydroxy-4-quinoloneHOD-cofactorfree-dioxygenase Natural | Quinoline
2-Heptylquinolin-4(1H)-oneHOD-cofactorfree-dioxygenase Natural | Quinoline
2-Monooleinabh_upf0017 Acyl-Glycerol | Natural
3-Methyl-3-butenyl-acetate Acetate | Natural
3-Oxoheptanoic-acidHydroxynitrile_lyase Fatty acid | Natural
4-AcetoxyphenolHormone-sensitive_lipase_like Aryl ester | Natural
4-DeoxyorobancholRsbQ-like Inden | Natural | Plant hormone | Strigolactone | Strigolactone receptors ligand
5-DeoxystrigolPlant_carboxylesterase | RsbQ-like Inden | Natural | Plant hormone | Strigolactone | Strigolactone receptors ligand
6-Tuliposide-APlant_carboxylesterase Carbohydrate | Natural
6-Tuliposide-BPlant_carboxylesterase Carbohydrate | Natural
6-monoacetylmorphineBCHE Alkaloid | Drug | Isoquinoline | Natural
7-Aminocephalosporanic-acidAcetyl-esterase_deacetylase | BD-FAE Antibiotic | Natural
AcetylcholineACHE | BCHE | Cholinesterase | Cholinesterase-like Acetate | Choline ester | Natural | Trimethylammonium
Alpha-amanitin-proproteinS9N_PPCE_Peptidase_S9 Macrocycle | Natural | Peptide | Toxin
Alpha-zearalenolZearalenone-hydrolase Macrolide | Mycotoxin-metabolite | Natural | Toxin
Benzyl-butyl-phthalateCutinase | Fungal_carboxylesterase_lipase Natural | Phthalate
Beta-zearalenolZearalenone-hydrolase Macrolide | Mycotoxin-metabolite | Natural | Toxin
BrefeldinAHormone-sensitive_lipase_like Antibiotic | Macrocycle | Natural | Toxin
CaffeoylshikimateMonoglyceridelipase_lysophospholip Natural
Cephalosporin-CAcetyl-esterase_deacetylase | BD-FAE | Homoserine_transacetylase Antibiotic | Natural
Chlorogenic-acidAlphaBeta_hydrolase | FaeC | Fungal_carboxylesterase_lipase | Hormone-sensitive_lipase_like | Monoglyceridelipase_lysophospholip | Plant_carboxylesterase | Tannase Hydroxycinnamic-ester | Natural
ChlorophyllChlorophyllase | Chlorophyllase_Plant | Pheophytinase Chlorophyll-like | Natural
CholesterolPC-sterol_acyltransferase Natural | Steroid
Cinnamic-acidAlphaBeta_hydrolase Natural
CocaineBCHE | Carb_B_Chordata | Cocaine_esterase Alkaloid | Benzoate | Drug | Natural
CoelenterazineHaloalkane_dehalogenase-HLD2 Luciferin | Natural
Coumarin-3-carboxylic-acid Coumarin | Natural
CutinAcetylxylan_esterase | Cutinase | Polyesterase-lipase-cutinase Natural | Polymer
DHDMPMpaH Benzofuran | Natural
DSHACarbon-carbon_bond_hydrolase Inden | Natural
Deacetylcephalosporin-CHomoserine_transacetylase Antibiotic | Natural
E-2-hexenyl-acetateCarb_B_Arthropoda | Plant_carboxylesterase Acetate | Natural | Plant volatile
Epicatechin-gallateAlphaBeta_hydrolase | Plant_carboxylesterase Benzoate | Derivative of Gallate | Natural | Polyphenol
Epigallocatechin-gallateAlphaBeta_hydrolase | Plant_carboxylesterase Benzoate | Derivative of Gallate | Natural | Polyphenol
Ethyl-cinnamateAlphaBeta_hydrolase | Lipase_3 Natural
Fumonisin-B1Carb_B_Bacteria Mycotoxin-metabolite | Natural | Toxin
Geranyl-acetateCanar_LipB | Carb_B_Arthropoda Acetate | Alkenyl ester | Natural | Plant volatile
Gibberellin-A3Plant_carboxylesterase Natural | Plant hormone
Gibberellin-A4Plant_carboxylesterase Natural | Plant hormone
GossypolCarb_B_Arthropoda Insecticide | Natural | Polyphenol
Hepoxilin-A3Epoxide_hydrolase Epoxide | Natural
Hepoxilin-B3Epoxide_hydrolase Epoxide | Natural
HeroinBCHE | Carb_B_Chordata Alkaloid | Drug | Isoquinoline | Natural
HexylacetateCarb_B_Arthropoda Acetate | Alkyl ester | Natural | Plant volatile
Juvenile-hormone-IIEpoxide_hydrolase Epoxide | Lactone | Natural
Juvenile-hormone-IIIEpoxide_hydrolase | Juvenile_hormone_esterase Epoxide | Lactone | Natural
Karrikin-1RsbQ-like Butenolide | Karrikin | Natural | Plant hormone | Strigolactone receptors ligand
Karrikin-2RsbQ-like Butenolide | Karrikin | Natural | Plant hormone | Strigolactone receptors ligand | desmethyl Strigolactone receptors ligand
Karrikin-3RsbQ-like Butenolide | Karrikin | Natural | Plant hormone | Strigolactone receptors ligand
Karrikin-4RsbQ-like Butenolide | Karrikin | Natural | Plant hormone | Strigolactone receptors ligand
MeGlcAGlucuronoyl_esterase Carbohydrate | Glucuronoyl | Natural
MeGlcA2Glucuronoyl_esterase Carbohydrate | Glucuronoyl | Natural
Methyl-farnesoateCarb_B_Arthropoda | Juvenile_hormone_esterase Natural
Methyl-salicylateHydroxynitrile_lyase Aryl ester | Benzoate | Natural | Plant hormone | Salicylic
Mycophenolic-acid-CoAMpaH Aminopurin | Benzofuran | CoA | Natural
Mycotoxin-T-2Carb_B_Chordata | Hormone-sensitive_lipase_like Mycotoxin-metabolite | Natural | Toxin
Myristic-acidPectinacetylesterase-Notum Fatty acid | Natural
N-acetylanthranilateHOD-cofactorfree-dioxygenase | Hormone-sensitive_lipase_like Benzoate | Natural
O-palmitoleoyl-L-serine Acyl peptide | Natural
ORFZ-SubstrateDuf_1100-S Mycotoxin-metabolite | Natural | Toxin
OctylacetateCarb_B_Arthropoda Acetate | Alkyl ester | Natural | Plant volatile
Oleoyl-CoACarb_B_Chordata | Carboxylesterase Aminopurin | CoA | Natural
Omphalotin-AS9N_PPCE_Peptidase_S9 Antibiotic | Macrolide | Natural | Peptide
OrobancholPlant_carboxylesterase | RsbQ-like Natural | Plant hormone | Strigolactone | Strigolactone receptors ligand
P(3HO)5_AlphaBeta_hydrolase | PHAZ7_phb_depolymerase Natural | Polyhydroxyalkanoate | Polymer
P(6HO)5_AlphaBeta_hydrolase Natural | Polyhydroxyalkanoate | Polymer
PAFLYsophospholipase_carboxylesterase | PAF-Acetylhydrolase Choline ester | Natural | Not A/B H target | Trimethylammonium | Water-insoluble medium and long chain ester
PGE2-glyceryl-esterABHD12-PHARC | ABHD6-Lip | Carb_B_Chordata | Monoglyceridelipase_lysophospholip Acyl-Glycerol | Cannabinoid-Receptor-ligand | Natural | Prostaglandin
PentagalloylglucosePlant_carboxylesterase Derivative of Gallate | Natural | Polyphenol
PhaeophytinChlorophyllase_Plant | Pheophytinase Chlorophyll-like | Natural
PimaricinThioesterase Antibiotic | Macrolide | Natural
Prostaglandin-D2-Glyceryl-EsterCarb_B_Chordata Acyl-Glycerol | Cannabinoid-Receptor-ligand | Natural | Prostaglandin
PyiE-SubstrateDuf_1100-S Mycotoxin-metabolite | Natural | Toxin
Retinol-acetate Acetate | Natural | Retinol ester
Retinol-oleateCholesterol_esterase | Pancreatic_lipase Natural | Retinol ester
Retinol-palmitateCarb_B_Chordata | Cholesterol_esterase | Fungal_carboxylesterase_lipase | Pancreatic_lipase Hexadecanoate | Natural | Retinol ester
RifampicinArylacetamide_deacetylase Acetate | Antibiotic | Drug | Natural | Not A/B H target
Rosmarinic-acidHormone-sensitive_lipase_like Hydroxycinnamic-ester | Natural
Skyllamycin-AThioesterase Antibiotic | Macrolide | Natural | Peptide
Skyllamycin-like-precursorThioesterase Antibiotic | Macrolide | Natural | Peptide
SorgolactoneRsbQ-like Inden | Natural | Plant hormone | Strigolactone | Strigolactone receptors ligand
StrigolRsbQ-like Inden | Natural | Plant hormone | Strigolactone | Strigolactone receptors ligand
Thiostrepton6_AlphaBeta_hydrolase Antibiotic | Macrocycle | Natural | Peptide | Quinoline
Tiancimycin-HTiancimycin-TnmK-Tripeptidase-HIP Antibiotic | Natural | Polyketide
Undecanoic-acidABHD6-Lip Fatty acid | Natural
Z-3-Hexenyl-acetateCarb_B_Arthropoda | Plant_carboxylesterase Acetate | Natural | Odorant | Plant volatile
ZearalenoneCarbon-carbon_bond_hydrolase | Zearalenone-hydrolase Macrolide | Mycotoxin-metabolite | Natural | Toxin
delta-hexadecalactone Hexadecanoate | Lactone | Natural | Pheromone

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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